Plasmodium chabaudi malaria parasites adjust liver stage development to synchronise egressing blood stages with host daily rhythms, aligning egress from the liver into the blood with the time of day of rhythmic host feeding.

Rodent model

Who

Plasmodium chabaudi parasites

What

When

Thu, 16 Jul 2026 14:19:39 GMT · 2h 50m ago

Where

Rodent model ·

Why

Aligning blood stage development with the feeding-fasting rhythm of the vertebrate host facilitates within-host survival and between-host transmission, enabling parasites to exploit the host’s food.

The Frontline Impact

How this affects you

This research reveals a mechanism by which malaria parasites adapt their life cycle to host daily rhythms, potentially influencing transmission dynamics and offering new avenues for therapeutic intervention targeting parasite synchronisation.

Story chain

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Verified Sources & Citations

Nature
https://www.nature.com/articles/s42003-026-10641-x?error=cookies_not_supported&code=34e91614-0281-4961-8307-019a76b0cc1e
HIGH

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