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Researchers at UNIFESP identified the syndecan-4 (SDC4) receptor on cancer cell surfaces, which, when overexpressed, protects tumor cells from programmed cell death.
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Federal University of São Paulo (UNIFESP), Brazil
Who
Researchers at the Federal University of São Paulo (UNIFESP) in Brazil, Carla Cristina Lopes, Bianca Zaia F. Ferreira
What
Researchers at UNIFESP identified the syndecan-4 (SDC4) receptor on cancer cell surfaces, which, when overexpressed, protects tumor cells from programmed cell death.
When
Thu, 18 Jun 2026 21:10:01 GMT · 14h 2m ago
Where
Federal University of São Paulo (UNIFESP), Brazil ·
Why
SDC4 overexpression allows tumor cells to evade anoikis, a specific type of cell death, enabling their survival and metastatic spread.
The Frontline Impact
How this affects you
The identification of SDC4 as a therapeutic target and diagnostic marker could lead to new strategies for preventing cancer cell proliferation and metastasis by silencing the molecule.
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