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Health & Science4d 4h ago

A new pico-calorimeter device, developed by Harvard researchers, can detect metabolic heat signals on the order of 100 picowatts in living cells, making it the most sensitive comparable bio-calorimeter to date.

Harvard John A. Paulson School of Engineering and Applied Sciences, United States

Who
Researchers in the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS); Joost Vlassak; Juanjuan Zheng
What
A new pico-calorimeter device, developed by Harvard researchers, can detect metabolic heat signals on the order of 100 picowatts in living cells, making it the most sensitive comparable bio-calorimeter to date.
When
Wed, 17 Jun 2026 04:49:00 GMT · 4d 4h ago
Where
Harvard John A. Paulson School of Engineering and Applied Sciences, United States ·
Why
The device can track the metabolism of small populations of bacteria in real time and monitor how bacterial growth changes in response to different antibiotics.
The Frontline Impact

How this affects you

This new pico-calorimeter could allow for faster and more direct detection of antibiotic resistance and cellular metabolism, potentially improving diagnostic methods for conditions like sepsis which often rely on slow, culture-based techniques. Such insights could lead to more effective treatments and better patient outcomes.

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