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Health & Science5h 21m ago
A new study by researchers at UC San Diego has identified a key genetic driver of cocaine addiction in the liver, rather than the brain, specifically linking the Ces1 gene cluster to compulsive cocaine addiction.
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UC San Diego
Who
Dr. Montana Kay Lara, Dr. Abraham A. Palmer, Dr. Olivier George, Miles Martin, UC San Diego, The Scripps Research Institute, Wake Forest University School of Medicine
What
A new study by researchers at UC San Diego has identified a key genetic driver of cocaine addiction in the liver, rather than the brain, specifically linking the Ces1 gene cluster to compulsive cocaine addiction.
When
Thu, 11 Jun 2026 20:45:22 GMT · 5h 21m ago
Where
UC San Diego ·
Why
The study aims to understand the biological mechanisms behind cocaine addiction to develop new treatment strategies.
The Frontline Impact
How this affects you
This research shifts the understanding of substance use disorder by demonstrating that peripheral metabolic processes in the liver significantly influence compulsive behavioral drives. It suggests that future medications could target liver enzymes to alter how the body metabolizes cocaine, potentially blunting the drive toward compulsive use and helping individuals genetically susceptible to addiction.
Story chain
2 events in this thread- Currently Reading5h 21m agoA new study by researchers at UC San Diego has identified a key genetic driver of cocaine addiction in the liver, rather than the brain, specifically linking the Ces1 gene cluster to compulsive cocaine addiction.
- Health & Science5h 21m agoA new study links the liver-based Ces1 gene cluster to compulsive cocaine addiction, offering a new treatment path.Open article