Back
63· Active
Health & Science2h 58m ago
UC Berkeley physicists have adapted the phase contrast technique to the electron microscope by adding a laser phase plate, greatly improving cryoelectron microscopy (cryo-EM).
Archive Window: 7 Days Left
UC Berkeley, Redwood City, California
Who
Holger Müller, Bridget Carragher, Stephani Otte
What
UC Berkeley physicists have adapted the phase contrast technique to the electron microscope by adding a laser phase plate, greatly improving cryoelectron microscopy (cryo-EM).
When
Mon, 15 Jun 2026 07:50:38 GMT · 2h 58m ago
Where
UC Berkeley, Redwood City, California ·
Why
The laser phase plate helps visualize smaller proteins and cellular structures that were previously too faint or challenging for biologists to study with traditional cryo-EM.
The Frontline Impact
How this affects you
This breakthrough allows for clearer images of molecules, including most human proteins down to one-third the size previously possible, and promises to revolutionize cryoelectron tomography (cryo-ET) by enabling the analysis of proteins in their natural cellular environment.
Story chain
4 events in this thread- Currently Reading2h 58m agoUC Berkeley physicists have adapted the phase contrast technique to the electron microscope by adding a laser phase plate, greatly improving cryoelectron microscopy (cryo-EM).
- Health & Science6h 24m agoResearchers in the United States have built a technology that boosts the performance of electron microscopes, adapting the phase-contrast technique to cryo-electron microscopy.Open article
- Health & Science6h 24m agoResearchers in the United States have built a technology that boosts the performance of electron microscopes.Open article
- Health & Science6h 24m agoResearchers in the United States have built a technology that boosts the performance of electron microscopes, offering detailed images of small molecules and cell structures.Open article